Some allergies, such as those to peanuts or shellfish, are becoming increasingly common. Others are still quite rare, affecting far fewer people around the world.

In fact, it is possible to be allergic to many different substances, some of which you might find surprising.

A recent episode ofGood Morning Americafocused on the little-known issue of an allergy to sperm.

The allergy, known officially as “seminal plasma hypersensitivity,” is estimated to affect 20,000 to 40,000 people in the U.S. And though cases of this unusual allergy have been reported for many years, the issue is only now receiving widespread attention.

Symptoms of Seminal Plasma Hypersensitivity

Symptoms of the allergy include loss of consciousness, dizziness, shortness of breath, wheezing, chest tightness, hives and swelling. Most women don’t realize that they have the allergy until they come into contact with semen for the first time.

Good Morning Americatalked to Clara, a woman who has the allergy. She says that she “had this bizarre reaction” the first time she came into contact with semen and “had burning and swelling and redness,” even when using a condom. Doctors thought she’d contracted an STD, but it turned out she was allergic to semen.

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