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No one knows precisely what causes fibromyalgia. Some possible triggers can sometimes include:

Using two separate drugs to shed weight can be very effective you will find combinations as you're watching FDA now awaiting approval. When dealing with weight loss and the people who go through it you need to err assisting caution and allow the FDA do its job and demand some research be done so that the public recognizes the side effects and dangers of the medications before we drive them. Keep in mind that drug companies will be in business to generate income and that they would say anything to keep people on the medications.

Researchers found that participants investing in this drug for any year, lost excess weight within one month and have kept the weight off through the 56 weeks from the study. Contrave is really a combination in the drugs naltrexone and bupropion, which generally seems to reflect a new trend of weight-loss drugs which are made up of several active ingredient, which can make them more effective and safer.

Combo-pilling will be the newest fad or better yet the newest into the future under scrutiny and so it is just more publicly known in recent months, comb-pilling for losing weight has been around since the eighties. The biggest reason that by using a combination of pills is starting to become popular is the fact that as of right now there are no long term prescription weight loss supplements that have been approved by the FDA besides orlistat. The truly disturbing part is doctors are prescribing these combinations of medications although some people might of the combinations are actually rejected or have yet to be licensed by the FDA.

Seizures can be a side effect with Contrave and really should not be taken in those with seizure disorders. The drug may also raise blood pressure and heart rate, and shouldn't be used in people who have a history of cardiac event or stroke in the last six months. Blood pressure and pulse should also be measured before commencing the drug and throughout therapy with the drug.

The FDA also warned that Contrave can raise hypertension and pulse rate and must not be used in patients with uncontrolled high hypertension, and also by you aren't heart-related and cerebrovascular (circulation dysfunction impacting your brain) disease. Patients having a history of cardiac arrest or stroke in the previous six months, life-threatening arrhythmias, or congestive heart failure were excluded from your clinical trials. Those taking Contrave needs to have their heart-rate and pulse monitored regularly. In addition, because the compound includes bupropion, Contrave comes with a boxed warning to alert health care professionals and patients towards the increased probability of suicidal thoughts and behaviors linked to antidepressant drugs. The warning also notes that serious neuropsychiatric events have been reported in patients taking bupropion for quitting smoking.

"This could be the first drug I'm mindful of that targets the two appetite and reward centres in the brain," he said.

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